Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM312187
Substrate
n/a
Meas. Tech.
Receptor Assay
Ki
2.12±0.75 nM
Citation
 McCurdy, CR; Mesangeau, C; Chin, FT; James, ML; Shen, B; Gambhir, S Highly selective sigma receptor radioligands US Patent  US9604926 Publication Date 3/28/2017 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_MOUSE | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
n/a
Mol. Mass.:
20818.69
Organism:
Mus musculus (Mouse)
Description:
Q8VD00
Residue:
176
Sequence:
MGALAARRCVEWLLGLYFVSHIPITLFIDLQAVLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLLCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAAHTITTLIPILYTLLFEDFSKAVAFKGQRPESFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM312187
Synonyms:
US9604926, Compound CM-325 | US9724435, Compound CM-325
Type:
Small organic molecule
Emp. Form.:
C27H35FN4O
Mol. Mass.:
450.5914
SMILES:
Fc1ccc(cc1)-n1c2ccccc2n(CCCCN2CCN(CC2)C2CCCCC2)c1=O
Structure:
Search PDB for entries with ligand similarity: