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Target
Proteinase-activated receptor 4
Ligand
BDBM175985
Substrate
n/a
Meas. Tech.
FLIPR Assay
EC50
2.50±n/a nM
Citation
 Kornacker, MG; Mapelli, C; Riexinger, DJ PAR4 agonist peptides US Patent  US9605024 Publication Date 3/28/2017 
Target
Name:
Proteinase-activated receptor 4
Synonyms:
Coagulation factor II receptor-like 3 | F2RL3 | PAR-4 | PAR4 | PAR4_HUMAN | Proteinase-activated receptor 4 | Proteinase-activated receptor 4 (PAR4) | Thrombin receptor-like 3
Type:
Protein
Mol. Mass.:
41145.16
Organism:
Homo sapiens (Human)
Description:
Q96RI0
Residue:
385
Sequence:
MWGRLLLWPLVLGFSLSGGTQTPSVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDTLELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLAAADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASHWQPAFTCLALLGCFLPLLAMLLCYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSNLLLLLHYSDPSPSAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSPGDTVASKASAEGGSRGMGTHSSLLQ
  
Inhibitor
Name:
BDBM175985
Synonyms:
US10047103, 18 | US9605024, Example 18 | US9688695, 18
Type:
Small organic molecule
Emp. Form.:
C25H20N4O5S2
Mol. Mass.:
520.58
SMILES:
COc1nn2cc(nc2s1)-c1cc2c(OCc3csc(n3)-c3ccc(OC)cc3)cc(OC)cc2o1
Structure:
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