Reaction Details Report a problem with these data
Target
Bromodomain-containing protein 3 [51-123]
Ligand
BDBM313793
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
<100±n/a nM
Citation
 Burns, C; Garnier, J; Sharp, PP; Feutrill, J; Cuzzupe, A Benzodiazepines as bromodomain inhibitors US Patent  US10167292 Publication Date 1/1/2019 
Target
Name:
Bromodomain-containing protein 3 [51-123]
Synonyms:
BRD3 | BRD3_HUMAN | Bromodomain-containing protein 3 (BRD3)(BD1) | Bromodomain-containing protein 3 Bromo 1 domain(BRD3 BD1) | KIAA0043 | RING3L
Type:
n/a
Mol. Mass.:
8887.10
Organism:
Homo sapiens (Human)
Description:
BD1 (51-123 aa) of Q15059
Residue:
73
Sequence:
WKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIV
  
Inhibitor
Name:
BDBM313793
Synonyms:
US10167292, Example 37
Type:
Small organic molecule
Emp. Form.:
C25H22ClN5O
Mol. Mass.:
443.928
SMILES:
Cc1nnn2CCN(c3ccc(Cl)cc3)c3cc(ccc3-c12)C(=O)NCc1ccccc1
Structure:
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