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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50077869
Substrate
n/a
Meas. Tech.
Binding Assay
Ki
97.4±n/a nM
Citation
 Torrens-Jover, A; Christmann, U; Diaz-Fernández, J; Almansa-Rosales, C 1,2,3-triazole-4-amine derivatives for the treatment of sigma receptor related diseases and disorders US Patent  US9611229 Publication Date 4/4/2017 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor, sigma 1 | Oprs1 | SGMR1_MOUSE | Sigma 1-type opioid receptor | Sigma1-receptor | Sigma1R | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25246.51
Organism:
Mus musculus (Mouse)
Description:
O55242
Residue:
223
Sequence:
MPWAAGRRWAWITLILTIIAVLIQAAWLWLGTQNFVFSREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCILHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWKEGTTKSEVFYPGETVVHGPGEATALEWGPNTWMVEYGRGVIPSTLFFALADTFFSTQDYLTLFYTLRAYARGLRLELTTYLFGQDS
  
Inhibitor
Name:
BDBM50077869
Synonyms:
CHEMBL3417078 | US9611229, 6
Type:
Small organic molecule
Emp. Form.:
C18H29N5O
Mol. Mass.:
331.4558
SMILES:
C(CN1CCOCC1)Nc1cn(nn1)C12CC3CC(CC(C3)C1)C2 |TLB:23:14:21:17.18.19,THB:19:18:15:21.20.22,19:20:17.18.23:15,23:18:21:14.15.22,11:14:21:17.18.19|
Structure:
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