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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM323594
Substrate
n/a
Meas. Tech.
Luciferase Assay
EC50
45.1±n/a nM
Citation
 Downes, M; Evans, R; Kluge, A; Lagu, B; Miura, M; Panigrahi, SK; Patane, M; Samajdar, S; Senaiar, R; Takahashi, T PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof US Patent  US10188627 Publication Date 1/29/2019 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Homo sapiens (Human)
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM323594
Synonyms:
(E)-6-(2-((N,2-dimethylbenzofuran-5-carboxamido)methyl) phenoxy)-4-methylhex-4-enoic acid | US10188627, Compound 8f
Type:
Small organic molecule
Emp. Form.:
C25H27NO5
Mol. Mass.:
421.4856
SMILES:
CN(Cc1ccccc1OC\C=C(/C)CCC(O)=O)C(=O)c1ccc2oc(C)cc2c1
Structure:
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