Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM312202
Substrate
n/a
Meas. Tech.
Receptor Assay
Ki
0.460±0.03 nM
Citation
 McCurdy, CR; Mesangeau, C; Chin, FT; James, ML; Shen, B; Gambhir, S; Biswal, S; Behera, D Highly selective sigma receptor ligands and radioligands as probes in nociceptive processing and the pathphysiological study of memory deficits and cognitive disorders US Patent  US9724435 Publication Date 8/8/2017 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
S2r | SGMR2_RAT | Sigma intracellular receptor 2 | Sigma-2 receptor | Sigma2 receptor | Tmem97 | Transmembrane protein 97
Type:
Protein
Mol. Mass.:
20953.88
Organism:
Rattus norvegicus (Rat)
Description:
Q5U3Y7
Residue:
176
Sequence:
MGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTITTLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFEEKRKKK
  
Inhibitor
Name:
BDBM312202
Synonyms:
US9604926, Compound CM-397 | US9724435, Compound CM-397
Type:
Small organic molecule
Emp. Form.:
C22H27FN4O
Mol. Mass.:
382.4744
SMILES:
Cn1c2ccccc2n(CCCCN2CCN(CC2)c2ccc(F)cc2)c1=O
Structure:
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