Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM163055
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Temperature
298.15±n/a K
IC50
>10000±n/a nM
Comments
extracted
Citation
 Chen, J; Pettit, S; Fliri, H Cannabinoid-2 agonists US Patent  US9670216 Publication Date 6/6/2017 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM163055
Synonyms:
US9062004, 20 | US9670216, 20 2-(3,5-Bistrifluoromethylphenyl)-4-chloro-5-propylaminopyridazin-3-one
Type:
Small organic molecule
Emp. Form.:
C15H12ClF6N3O
Mol. Mass.:
399.719
SMILES:
CCCNc1cnn(-c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(=O)c1Cl
Structure:
Search PDB for entries with ligand similarity: