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Target
Amyloid beta-binding alcohol dehydrogenase
Ligand
BDBM232928
Substrate
n/a
Meas. Tech.
Assay of ABAD Enzymatic Activity
IC50
7200±n/a nM
Citation
 Yan, S; Valasani, KR Phosphonate derivatives and methods of use thereof in the treatment of Alzheimer's disease US Patent  US9738668 Publication Date 8/22/2017 
Target
Name:
Amyloid beta-binding alcohol dehydrogenase
Synonyms:
Amyloid beta-binding alcohol dehydrogenase (ABAD)
Type:
Enzyme
Mol. Mass.:
938.17
Organism:
Homo sapiens (Human)
Description:
Q2L8D9
Residue:
9
Sequence:
MAAACRSVK
  
Inhibitor
Name:
BDBM232928
Synonyms:
US9346839, 9 | US9738668, Compound 9
Type:
Small organic molecule
Emp. Form.:
C17H19N2O5PS
Mol. Mass.:
394.382
SMILES:
COc1ccc2nc(N[C@@H](c3ccccc3O)P(=O)(OC)OC)sc2c1 |r|
Structure:
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