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Target
P2Y purinoceptor 1
Ligand
BDBM260967
Substrate
n/a
Meas. Tech.
Scintillation Proximity Assay (SPA)
pH
7.4±n/a
Temperature
298.15±n/a K
Ki
13±n/a nM
Comments
extracted
Citation
 LHeureux, A 7-hydroxy-indolinyl antagonists of P2Y1 receptor US Patent  US9540323 Publication Date 1/10/2017 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM260967
Synonyms:
US9540323, 167 | US9540323, example 167
Type:
Small organic molecule
Emp. Form.:
C27H20Cl2FN5O2S2
Mol. Mass.:
600.514
SMILES:
CC1(C)CN(c2c1c(-c1nc3cc(Cl)ccc3s1)c(F)cc2O)c1ccccc1NC(=O)Nc1csc(Cl)n1
Structure:
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