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Target
P2Y purinoceptor 1
Ligand
BDBM261035
Substrate
n/a
Meas. Tech.
Scintillation Proximity Assay (SPA)
pH
7.4±n/a
Temperature
298.15±n/a K
Ki
6.60±n/a nM
Comments
extracted
Citation
 LHeureux, A 7-hydroxy-indolinyl antagonists of P2Y1 receptor US Patent  US9540323 Publication Date 1/10/2017 
Target
Name:
P2Y purinoceptor 1
Synonyms:
ATP receptor | P2RY1 | P2RY1_HUMAN | P2Y purinoceptor 1 (P2Y1) | P2Y1 | Purinergic receptor | Purinergic receptor P2Y1
Type:
Enzyme
Mol. Mass.:
42090.25
Organism:
Homo sapiens (Human)
Description:
P47900
Residue:
373
Sequence:
MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL
  
Inhibitor
Name:
BDBM261035
Synonyms:
US9540323, 256 | US9540323, example 256
Type:
Small organic molecule
Emp. Form.:
C29H27F4N5O4
Mol. Mass.:
585.5494
SMILES:
CC(C)c1noc(n1)-c1c2c(N(CC2(C)C)c2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)c(O)cc1F
Structure:
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