Target

Ligand

Substrate

Meas. Tech.

PDF Inhibition Assay

pH

7.6±n/a

Temperature

298.15±n/a K

Citation

 Smith, KJ; Petit, CM; Aubart, K; Smyth, M; McManus, E; Jones, J; Fosberry, A; Lewis, C; Lonetto, M; Christensen, SB Structural variation and inhibitor binding in polypeptide deformylase from four different bacterial species. Protein Sci 12:349-60 (2003) [PubMed]  Article Copy BDB DOI

More Info.:

Get all data from this article,  Inhibition_Run data,   Solution Info,  Assay Method

Name:

Peptide deformylase

Synonyms:

DEF_ECOLI | PDF | Peptide Deformylase | Polypeptide deformylase | def | fms

Type:

Enzyme

Mol. Mass.:

19323.16

Organism:

Escherichia coli (strain K12)

Description:

The pdf gene from E. coli K12 was cloned and protein was expressed and purified from E. coli BL21(DE3).

Residue:

169

Sequence:

MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA

Blast this sequence in BindingDB or PDB

  
Blast E-value cutoff:

Name:

BDBM21684

Synonyms:

N-[2-(3-benzoylphenoxy)ethyl]-N-hydroxyformamide | SB-543668

Type:

Small organic molecule

Emp. Form.:

C16H15NO4

Mol. Mass.:

285.2946

SMILES:

ON(CCOc1cccc(c1)C(=O)c1ccccc1)C=O

Structure:

Search PDB for entries with ligand similarity:

Similarity to this molecule at least:

Name:

PDF substrate peptide

Synonyms:

n/a

Type:

Peptide

Mol. Mass.:

1718.01

Organism:

n/a

Description:

n/a

Residue:

14

Sequence:

FRMYLMETALASER