Reaction Details Report a problem with these data
Target
Platelet glycoprotein 4
Ligand
BDBM50395016
Substrate
n/a
Meas. Tech.
Receptor Binding Assay with 125I-Ghrelin
pH
7.3±n/a
IC50
4940±n/a nM
Comments
extracted
Citation
 Ong, H; Chemtob, S; Lubell, W; Sennlaub, F; Boeglin, D; Proulx, C; Sajjadi, Z; Sabatino, D Azapeptides as CD36 binding compounds US Patent  US9708370 Publication Date 7/18/2017 
Target
Name:
Platelet glycoprotein 4
Synonyms:
Adipocyte membrane protein | CD36_RAT | CD_antigen=CD36 | Cd36 | Fat | Fatty acid translocase | Fatty acid transport protein | GPIIIB | GPIV | Glycoprotein IIIb | PAS IV | PAS-4 | Platelet glycoprotein IV
Type:
PROTEIN
Mol. Mass.:
52740.95
Organism:
Rattus norvegicus
Description:
ChEMBL_858884
Residue:
472
Sequence:
MGCDRNCGLITGAVIGAVLAVFGGILMPVGDLLIEKTIKREVVLEEGTIAFKNWVKTGTTVYRQFWIFDVQNPEEVAKNSSKIKVKQRGPYTYRVRYLAKENITQDPKDSTVSFVQPNGAIFEPSLSVGTENDNFTVLNLAVAAAPHIYTNSFVQGVLNSLIKKSKSSMFQTRSLKELLWGYKDPFLSLVPYPISTTVGVFYPYNNTVDGVYKVFNGKDNISKVAIIDTYKGKRNLSYWESYCDMINGTDAASFPPFVEKSQTLRFFSSDICRSIYAVFESEVNLKGIPVYRFVLPANAFASPLQNPDNHCFCTEKVISNNCTSYGVLDIGKCKEGKPVYISLPHFLHASPDVSEPIEGLNPNEDEHRTYLDVEPITGFTLQFAKRLQVNILVKPARKIEALKNLKRPYIVPILWLNETGTIGDEKAEMFRNQVTGKIKLLGLVEMVLLGVGVVMFVAFMISYCACRSKNGK
  
Inhibitor
Name:
BDBM50395016
Synonyms:
CHEMBL2163452 | US9708370, CP-2B(ii)
Type:
Small organic molecule
Emp. Form.:
C42H57N13O6
Mol. Mass.:
839.9855
SMILES:
CC(C)CN(NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C)C(=O)N[C@@H](CCCCN)C(N)=O |r|
Structure:
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