Reaction Details Report a problem with these data
Target
Glyceraldehyde-3-phosphate dehydrogenase, cytosolic
Ligand
BDBM65497
Substrate
n/a
Meas. Tech.
cytomteric bead array (CBA) assay
Temperature
310.15±n/a K
IC50
>10000±n/a nM
Comments
extracted
Citation
 Gandhi, A; Dimartino, J; Chopra, R Methods for the treatment of locally advanced breast cancer US Patent  US9694015 Publication Date 7/4/2017 
Target
Name:
Glyceraldehyde-3-phosphate dehydrogenase, cytosolic
Synonyms:
G3PC_LEIME | GAPC | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase cytosolic | Glyceraldehyde-3-phosphate dehydrogenase, cytosolic
Type:
PROTEIN
Mol. Mass.:
35645.40
Organism:
Leishmania mexicana
Description:
ChEMBL_72768
Residue:
331
Sequence:
MVKVGINGFGRIGRVVFRAAQMRPDIEIVGINDLLDAEYMAYSLKYDSTHGRFDGTVEVIKGALVVNGKSIRVTSERDPANLKWDEIGVEVVVESTGLFLTQETAHKHIEAGARRVVMTGPPKDDTPMFVMGVNHTTYKGQPIISNASCTTNCLAPLAKVVNEKYGIVEGLMTTVHATTATQKTVDGPSLKDWRGGRGASQNIIPSSTGAPKAVGKVYPALDGKLTGMAFRVPTPNVSVVDLTVRLEKPATYKDICAAIKAAAEGEMKGILGYTDDEVVSSDFNGVALTSVFDVKAGISLNDHFVKLVSWYDNETGYSHKVLDLILHTSAR
  
Inhibitor
Name:
BDBM65497
Synonyms:
CC-220 (Compound 6) | US9694015, 6.4S
Type:
Small organic molecule
Emp. Form.:
C25H27N3O5
Mol. Mass.:
449.499
SMILES:
O=C1N(Cc2c1cccc2OCc1ccc(CN2CCOCC2)cc1)[C@H]1CCC(=O)NC1=O
Structure:
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