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Target
Granulocyte-macrophage colony-stimulating factor
Ligand
BDBM76986
Substrate
n/a
Meas. Tech.
cytomteric bead array (CBA) assay
Temperature
310.15±n/a K
IC50
950±n/a nM
Comments
extracted
Citation
 Gandhi, A; Dimartino, J; Chopra, R Methods for the treatment of locally advanced breast cancer US Patent  US9694015 Publication Date 7/4/2017 
Target
Name:
Granulocyte-macrophage colony-stimulating factor
Synonyms:
CSF | CSF2 | CSF2_HUMAN | Colony-stimulating factor | GM-CSF | GMCSF | Molgramostin | Sargramostim
Type:
Protein
Mol. Mass.:
16291.07
Organism:
Homo sapiens (Human)
Description:
P04141
Residue:
144
Sequence:
MWLQSLLLLGTVACSISAPARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVISEMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLTMMASHYKQHCPPTPETSCATQIITFESFKENLKDFLLVIPFDCWEPVQE
  
Inhibitor
Name:
BDBM76986
Synonyms:
3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione | US11059801, Compound D-17 | US9694015, Compound A
Type:
Small organic molecule
Emp. Form.:
C14H14N4O3
Mol. Mass.:
286.286
SMILES:
Cc1nc2cccc(N)c2c(=O)n1C1CCC(=O)NC1=O
Structure:
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