Reaction Details Report a problem with these data
Target
C-C motif chemokine 4
Ligand
BDBM50070114
Substrate
n/a
Meas. Tech.
cytomteric bead array (CBA) assay
Temperature
310.15±n/a K
IC50
>10000±n/a nM
Comments
extracted
Citation
 Gandhi, A; Dimartino, J; Chopra, R Methods for the treatment of locally advanced breast cancer US Patent  US9694015 Publication Date 7/4/2017 
Target
Name:
C-C motif chemokine 4
Synonyms:
ACT-2 | CCL4 | CCL4_HUMAN | G-26 T-lymphocyte-secreted protein | HC21 | LAG-1 | LAG1 | Lymphocyte activation gene 1 protein | MIP-1-beta | MIP1B | Macrophage inflammatory protein 1-beta | PAT 744 | Protein H400 | SCYA4 | SIS-gamma | Small-inducible cytokine A4 | T-cell activation protein 2
Type:
Protein
Mol. Mass.:
10210.74
Organism:
Homo sapiens (Human)
Description:
P13236
Residue:
92
Sequence:
MKLCVTVLSLLMLVAAFCSPALSAPMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQPAVVFQTKRSKQVCADPSESWVQEYVYDLELN
  
Inhibitor
Name:
BDBM50070114
Synonyms:
(+/-)-thalidomide | 2-(2,6-Dioxo-piperidin-3-yl)-isoindole-1,3-dione | 2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione | CHEMBL468 | K-17 | THALIDOMIDE | Thalomid | US11059801, Compound D-62 | [(R,S)-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Type:
Small organic molecule
Emp. Form.:
C13H10N2O4
Mol. Mass.:
258.2295
SMILES:
O=C1N(C2CCC(=O)NC2=O)C(=O)c2ccccc12
Structure:
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