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Target
N-formyl peptide receptor 2
Ligand
BDBM391983
Substrate
n/a
Meas. Tech.
FLIPR assay
EC50
4.00±n/a nM
Citation
 Beard, RL; Duong, TT; Garst, ME Imidazole derivatives as formyl peptide receptor modulators US Patent  US10301269 Publication Date 5/28/2019 
Target
Name:
N-formyl peptide receptor 2
Synonyms:
ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
38968.35
Organism:
Homo sapiens (Human)
Description:
P25090
Residue:
351
Sequence:
METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
  
Inhibitor
Name:
BDBM391983
Synonyms:
1-[(1S)-1-(1H-imidazol- 2-yl)-2-methylpropyl]- 3-[4- (trifluoromethyl)phenyl] urea | US10301269, Number 28 | US10800744, Number 28
Type:
Small organic molecule
Emp. Form.:
C15H17F3N4O
Mol. Mass.:
326.3169
SMILES:
CC(C)[C@H](NC(=O)Nc1ccc(cc1)C(F)(F)F)c1ncc[nH]1 |r|
Structure:
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