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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50153593
Substrate
n/a
Meas. Tech.
MAO-B Inhibitory Assay
pH
7.5±n/a
Temperature
298.15±n/a K
IC50
>100000±n/a nM
Comments
extracted
Citation
 Matsumoto, S; Hattori, Y; Toyofuku, M; Morimoto, S; Kojima, T; Kaku, T; Ito, M Cyclopropanamine compound and use thereof US Patent  US9714241 Publication Date 7/25/2017 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50153593
Synonyms:
CHEMBL3775351 | US10053456, 123 | US10414761, Example 123 | US10968213, Example 123 | US9487511, 123 | US9718814, 123 | US9920047, 123
Type:
Small organic molecule
Emp. Form.:
C17H22N4OS
Mol. Mass.:
330.448
SMILES:
Cc1sc(cc1[C@@H]1C[C@H]1NC1CCC1)C(=O)Nc1cnn(C)c1 |r|
Structure:
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