Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36823
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Potentiator Assay 60K MLSMR
EC50
14840±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Potentiator Assay 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36823
Synonyms:
2-Ethoxy-3-(5-furan-2-yl-[1,2,4]oxadiazol-3-yl)-6-phenyl-pyridine | 3-(2-ethoxy-6-phenyl-3-pyridinyl)-5-(2-furanyl)-1,2,4-oxadiazole | 3-(2-ethoxy-6-phenyl-3-pyridyl)-5-(2-furyl)-1,2,4-oxadiazole | 3-(2-ethoxy-6-phenyl-pyridin-3-yl)-5-(furan-2-yl)-1,2,4-oxadiazole | 3-(2-ethoxy-6-phenylpyridin-3-yl)-5-(furan-2-yl)-1,2,4-oxadiazole | MLS000071123 | SMR000014898 | cid_645766
Type:
Small organic molecule
Emp. Form.:
C19H15N3O3
Mol. Mass.:
333.3407
SMILES:
CCOc1nc(ccc1-c1noc(n1)-c1ccco1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: