Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36854
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Potentiator Assay 60K MLSMR
EC50
>95000±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Potentiator Assay 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36854
Synonyms:
MLS000074457 | N-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-2-(6-methyl-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-acetamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(3-keto-6-methyl-1,4-benzoxazin-4-yl)acetamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(6-methyl-3-oxidanylidene-1,4-benzoxazin-4-yl)ethanamide | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(6-methyl-3-oxo-1,4-benzoxazin-4-yl)acetamide | SMR000007339 | cid_650930
Type:
Small organic molecule
Emp. Form.:
C19H18N2O5
Mol. Mass.:
354.3566
SMILES:
Cc1ccc2OCC(=O)N(CC(=O)Nc3ccc4OCCOc4c3)c2c1
Structure:
Search PDB for entries with ligand similarity: