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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36820
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
53200±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36820
Synonyms:
3-Ethyl-2-[(Z)-ethylimino]-4-oxo-3,4-dihydro-2H-[1,3]thiazine-6-carboxylic acid phenethyl-amide | 3-ethyl-2-ethylimino-4-keto-N-phenethyl-1,3-thiazine-6-carboxamide | 3-ethyl-2-ethylimino-4-oxidanylidene-N-(2-phenylethyl)-1,3-thiazine-6-carboxamide | 3-ethyl-2-ethylimino-4-oxo-N-(2-phenylethyl)-1,3-thiazine-6-carboxamide | MLS000075579 | SMR000014375 | cid_645206
Type:
Small organic molecule
Emp. Form.:
C17H21N3O2S
Mol. Mass.:
331.433
SMILES:
CC\N=c1/sc(cc(=O)n1CC)C(=O)NCCc1ccccc1
Structure:
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