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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36828
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>95100±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36828
Synonyms:
2-(2-furoylamino)-1,3-benzothiazole-6-carboxylic acid ethyl ester | 2-[(Furan-2-carbonyl)-amino]-benzothiazole-6-carboxylic acid ethyl ester | 2-[[2-furanyl(oxo)methyl]amino]-1,3-benzothiazole-6-carboxylic acid ethyl ester | MLS000034531 | SMR000013744 | cid_646260 | ethyl 2-(furan-2-carbonylamino)-1,3-benzothiazole-6-carboxylate | ethyl 2-(furan-2-ylcarbonylamino)-1,3-benzothiazole-6-carboxylate
Type:
Small organic molecule
Emp. Form.:
C15H12N2O4S
Mol. Mass.:
316.332
SMILES:
CCOC(=O)c1ccc2nc(NC(=O)c3ccco3)sc2c1
Structure:
Search PDB for entries with ligand similarity: