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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36830
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>95100±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36830
Synonyms:
2-[3-keto-6-[(2-methoxyphenyl)carbamoyl]-2,2-dimethyl-1,4-benzoxazin-4-yl]acetic acid ethyl ester | 2-[6-[(2-methoxyanilino)-oxomethyl]-2,2-dimethyl-3-oxo-1,4-benzoxazin-4-yl]acetic acid ethyl ester | MLS000068354 | SMR000006960 | [6-(2-Methoxy-phenylcarbamoyl)-2,2-dimethyl-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl]-acetic acid ethyl ester | cid_646770 | ethyl 2-[6-[(2-methoxyphenyl)carbamoyl]-2,2-dimethyl-3-oxidanylidene-1,4-benzoxazin-4-yl]ethanoate | ethyl 2-[6-[(2-methoxyphenyl)carbamoyl]-2,2-dimethyl-3-oxo-1,4-benzoxazin-4-yl]acetate
Type:
Small organic molecule
Emp. Form.:
C22H24N2O6
Mol. Mass.:
412.4358
SMILES:
CCOC(=O)CN1C(=O)C(C)(C)Oc2ccc(cc12)C(=O)Nc1ccccc1OC
Structure:
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