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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM36858
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
4080±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM36858
Synonyms:
1-[[(Z)-2-bromanyl-3-phenyl-prop-2-enylidene]amino]-1,2,3,4-tetrazol-5-amine | 1-[[(Z)-2-bromo-3-phenylprop-2-enylidene]amino]-5-tetrazolamine | 1-[[(Z)-2-bromo-3-phenylprop-2-enylidene]amino]tetrazol-5-amine | MLS000072878 | N*1*-[(Z)-2-Bromo-3-phenyl-prop-2-en-(E)-ylidene]-tetrazole-1,5-diamine | SMR000001159 | [1-[[(Z)-2-bromo-3-phenyl-prop-2-enylidene]amino]tetrazol-5-yl]amine | cid_840845
Type:
Small organic molecule
Emp. Form.:
C10H9BrN6
Mol. Mass.:
293.123
SMILES:
Nc1nnnn1N=C\C(Br)=C\c1ccccc1 |w:6.6|
Structure:
Search PDB for entries with ligand similarity: