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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM37176
Substrate
n/a
Meas. Tech.
Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Parental Cell Line Counter Screen 60K MLSMR PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM37176
Synonyms:
(5-amino-3-methyl-4-phenyl-1-pyrazolyl)-thiophen-2-ylmethanone | (5-amino-3-methyl-4-phenyl-pyrazol-1-yl)-(2-thienyl)methanone | (5-amino-3-methyl-4-phenylpyrazol-1-yl)-thiophen-2-ylmethanone | (5-azanyl-3-methyl-4-phenyl-pyrazol-1-yl)-thiophen-2-yl-methanone | MLS000115895 | SMR000092900 | cid_1263277
Type:
Small organic molecule
Emp. Form.:
C15H13N3OS
Mol. Mass.:
283.348
SMILES:
Cc1nn(C(=O)c2cccs2)c(N)c1-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: