Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM37787
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
IC50
30300±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37787
Synonyms:
1-allyl-2-(butylthio)-6-hydroxy-pyrimidin-4-one | 2-(butylthio)-6-hydroxy-1-prop-2-enyl-4-pyrimidinone | 2-butylsulfanyl-6-hydroxy-1-prop-2-enylpyrimidin-4-one | 2-butylsulfanyl-6-oxidanyl-1-prop-2-enyl-pyrimidin-4-one | MLS000114539 | SMR000091904 | cid_1618319
Type:
Small organic molecule
Emp. Form.:
C11H16N2O2S
Mol. Mass.:
240.322
SMILES:
CCCCSc1nc(O)cc(=O)n1CC=C
Structure:
Search PDB for entries with ligand similarity: