Reaction Details Report a problem with these data
Target
Diphosphomevalonate decarboxylase
Ligand
BDBM38366
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response
IC50
2145.5±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Diphosphomevalonate decarboxylase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
35571.44
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZN59
Residue:
317
Sequence:
MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYTETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAAGLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEIYPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLKENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMDAGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC
  
Inhibitor
Name:
BDBM38366
Synonyms:
2-(4-piperidin-1-ylsulfonylphenyl)-1,2-benzothiazol-3-one | 2-(4-piperidinosulfonylphenyl)-1,2-benzothiazol-3-one | 2-[4-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-one | MLS000054457 | SMR000060795 | cid_2327941
Type:
Small organic molecule
Emp. Form.:
C18H18N2O3S2
Mol. Mass.:
374.477
SMILES:
O=c1n(sc2ccccc12)-c1ccc(cc1)S(=O)(=O)N1CCCCC1
Structure:
Search PDB for entries with ligand similarity: