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Target
Mevalonate kinase
Ligand
BDBM34579
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
8716.8±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM34579
Synonyms:
4-[[cyclohexyl(methyl)amino]methyl]-3-hydroxy-6-benzo[c][1]benzopyranone | 4-[[cyclohexyl(methyl)amino]methyl]-3-hydroxy-benzo[c]chromen-6-one | 4-[[cyclohexyl(methyl)amino]methyl]-3-hydroxybenzo[c]chromen-6-one | 4-[[cyclohexyl(methyl)amino]methyl]-3-oxidanyl-benzo[c]chromen-6-one | MLS000027386 | SMR000036026 | cid_5389209
Type:
Small organic molecule
Emp. Form.:
C21H23NO3
Mol. Mass.:
337.4122
SMILES:
CN(Cc1c(O)ccc2c3ccccc3c(=O)oc12)C1CCCCC1
Structure:
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