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Target
Alkaline phosphatase, germ cell type
Ligand
BDBM39711
Substrate
n/a
Meas. Tech.
Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase
IC50
20400±1660 nM
Citation
 PubChem, PC Luminescent assay for HTS discovery of chemical inhibitors of placental alkaline phosphatase PubChem Bioassay (2007)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM39711
Synonyms:
4-[2-(1,3-dihydrobenzimidazol-2-ylidene)-3-keto-3-(2-thienyl)propylidene]-2,6-dimethoxy-cyclohexa-2,5-dien-1-one | 4-[2-(1,3-dihydrobenzimidazol-2-ylidene)-3-oxidanylidene-3-thiophen-2-yl-propylidene]-2,6-dimethoxy-cyclohexa-2,5-dien-1-one | 4-[2-(1,3-dihydrobenzimidazol-2-ylidene)-3-oxo-3-thiophen-2-ylpropylidene]-2,6-dimethoxy-1-cyclohexa-2,5-dienone | 4-[2-(1,3-dihydrobenzimidazol-2-ylidene)-3-oxo-3-thiophen-2-ylpropylidene]-2,6-dimethoxycyclohexa-2,5-dien-1-one | MLS000564302 | SMR000151825 | cid_5972274
Type:
Small organic molecule
Emp. Form.:
C22H18N2O4S
Mol. Mass.:
406.454
SMILES:
COc1cc(C=C(C(=O)c2cccs2)c2nc3ccccc3[nH]2)cc(OC)c1O
Structure:
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