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Target
14-3-3 protein gamma
Ligand
BDBM32001
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
>50000±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM32001
Synonyms:
7-Oxo-7H-benzo[e]perimidine-4-carboxylic acid | 7-ketobenzo[e]perimidine-4-carboxylic acid | 7-oxidanylidenebenzo[e]perimidine-4-carboxylic acid | 7-oxo-4-benzo[e]perimidinecarboxylic acid | 7-oxobenzo[e]perimidine-4-carboxylic acid | CHEMBL166209 | MLS000077061 | SMR000008738 | cid_72574
Type:
Small organic molecule
Emp. Form.:
C16H8N2O3
Mol. Mass.:
276.2463
SMILES:
OC(=O)c1ccc2C(=O)c3ccccc3-c3ncnc1c23
Structure:
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