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Target
14-3-3 protein gamma
Ligand
BDBM32003
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
5022.5±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM32003
Synonyms:
2-(2-hydroxy-9-keto-5H-benzo[b][1,4]benzoxazepin-6-yl)benzoic acid | 2-(2-hydroxy-9-oxo-5H-benzo[b][1,4]benzoxazepin-6-yl)benzoic acid | 2-(2-oxidanyl-9-oxidanylidene-5H-benzo[b][1,4]benzoxazepin-6-yl)benzoic acid | 2-(3,7-Dihydroxy-dibenzo[b,f][1,4]oxazepin-11-yl)-benzoic acid | MLS000077269 | SMR000009634 | cid_5405444
Type:
Small organic molecule
Emp. Form.:
C20H13NO5
Mol. Mass.:
347.3209
SMILES:
OC(=O)c1ccccc1C1=Nc2ccc(O)cc2Oc2cc(O)ccc12 |t:10|
Structure:
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