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Target
14-3-3 protein gamma
Ligand
BDBM39858
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
>50000±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM39858
Synonyms:
MLS000070519 | N-(2,5-Dimethoxy-phenyl)-3-(3-methyl-piperidin-1-yl)-propionamide | N-(2,5-dimethoxyphenyl)-3-(3-methyl-1-piperidinyl)propanamide;hydrochloride | N-(2,5-dimethoxyphenyl)-3-(3-methylpiperidin-1-yl)propanamide;hydrochloride | N-(2,5-dimethoxyphenyl)-3-(3-methylpiperidino)propionamide;hydrochloride | SMR000011889 | cid_2900388
Type:
Small organic molecule
Emp. Form.:
C17H26N2O3
Mol. Mass.:
306.3999
SMILES:
COc1ccc(OC)c(NC(=O)CCN2CCCC(C)C2)c1
Structure:
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