Reaction Details Report a problem with these data
Target
14-3-3 protein gamma
Ligand
BDBM39866
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
>50000±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM39866
Synonyms:
2-(2-furanylmethylideneamino)-6-methyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide | 2-(2-furfurylideneamino)-6-methyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide | 2-(furan-2-ylmethylideneamino)-6-methyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide | MLS000079969 | SMR000039963 | cid_658933
Type:
Small organic molecule
Emp. Form.:
C14H15N3O2S
Mol. Mass.:
289.353
SMILES:
CN1CCc2c(C1)sc(N=Cc1ccco1)c2C(N)=O |w:9.9|
Structure:
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