Reaction Details Report a problem with these data
Target
14-3-3 protein gamma
Ligand
BDBM39871
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
>50000±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM39871
Synonyms:
3-butyl-2-keto-5-(morpholinomethyl)tetrahydrofuran-3-carboxylic acid ethyl ester | 3-butyl-5-(4-morpholinylmethyl)-2-oxo-3-oxolanecarboxylic acid ethyl ester | MLS000037648 | SMR000034771 | cid_661019 | ethyl 3-butyl-5-(morpholin-4-ylmethyl)-2-oxidanylidene-oxolane-3-carboxylate | ethyl 3-butyl-5-(morpholin-4-ylmethyl)-2-oxooxolane-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C16H27NO5
Mol. Mass.:
313.3893
SMILES:
CCCCC1(CC(CN2CCOCC2)OC1=O)C(=O)OCC
Structure:
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