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Target
14-3-3 protein gamma
Ligand
BDBM39872
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
>50000±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM39872
Synonyms:
1-hydroxy-3-phenyl-1-(3,4,4-trimethyl-2-sulfanylidene-1,3-thiazolidin-5-yl)urea | 1-hydroxy-3-phenyl-1-(3,4,4-trimethyl-2-sulfanylidene-5-thiazolidinyl)urea | 1-hydroxy-3-phenyl-1-(3,4,4-trimethyl-2-thioxo-thiazolidin-5-yl)urea | 1-oxidanyl-3-phenyl-1-(3,4,4-trimethyl-2-sulfanylidene-1,3-thiazolidin-5-yl)urea | MLS000028325 | SMR000042066 | cid_661438
Type:
Small organic molecule
Emp. Form.:
C13H17N3O2S2
Mol. Mass.:
311.423
SMILES:
CN1C(=S)SC(N(O)C(=O)Nc2ccccc2)C1(C)C
Structure:
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