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Target
14-3-3 protein gamma
Ligand
BDBM39880
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
7294.5±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM39880
Synonyms:
1-(ethylamino)-3-methyl-3H-naphtho[1,2,3-de]quinoline-2,7-dione | MLS000043530 | SMR000020347 | cid_712714
Type:
Small organic molecule
Emp. Form.:
C19H16N2O2
Mol. Mass.:
304.3425
SMILES:
CCNc1c2-c3ccccc3C(=O)c3cccc(n(C)c1=O)c23
Structure:
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