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Target
14-3-3 protein gamma
Ligand
BDBM37111
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
>50000±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM37111
Synonyms:
5-[(6-bromanyl-1,3-benzodioxol-5-yl)methylsulfanyl]-1-(2-methoxyphenyl)-1,2,3,4-tetrazole | 5-[(6-bromo-1,3-benzodioxol-5-yl)methylsulfanyl]-1-(2-methoxyphenyl)tetrazole | 5-[(6-bromo-1,3-benzodioxol-5-yl)methylthio]-1-(2-methoxyphenyl)tetrazole | 5-{[(6-bromo-1,3-benzodioxol-5-yl)methyl]thio}-1-(2-methoxyphenyl)-1H-tetrazole | MLS000051400 | SMR000079575 | cid_1253064
Type:
Small organic molecule
Emp. Form.:
C16H13BrN4O3S
Mol. Mass.:
421.268
SMILES:
COc1ccccc1-n1nnnc1SCc1cc2OCOc2cc1Br
Structure:
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