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Target
14-3-3 protein gamma
Ligand
BDBM39882
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
>50000±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM39882
Synonyms:
1-(2-keto-7,7-dimethyl-norbornan-1-yl)-N,N-dimethyl-methanesulfonamide | 1-(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)-N,N-dimethylmethanesulfonamide | 1-(7,7-dimethyl-3-oxidanylidene-4-bicyclo[2.2.1]heptanyl)-N,N-dimethyl-methanesulfonamide | 1-(7,7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl)-N,N-dimethylmethanesulfonamide | MLS000096856 | SMR000074569 | cid_2946887
Type:
Small organic molecule
Emp. Form.:
C12H21NO3S
Mol. Mass.:
259.365
SMILES:
[H]C12CCC(CS(=O)(=O)N(C)C)(C(=O)C1)C2(C)C |TLB:13:12:15:3.2|
Structure:
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