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Target
14-3-3 protein gamma
Ligand
BDBM39883
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
>50000±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM39883
Synonyms:
2,6-dibenzyl-5-methyl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | 2,6-dibenzyl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one | 5-methyl-2,6-bis(phenylmethyl)-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | MLS000066086 | SMR000079590 | cid_1253200
Type:
Small organic molecule
Emp. Form.:
C20H18N4O
Mol. Mass.:
330.3831
SMILES:
Cc1nc2nc(Cc3ccccc3)[nH]n2c(=O)c1Cc1ccccc1
Structure:
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