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Target
14-3-3 protein gamma
Ligand
BDBM39888
Substrate
n/a
Meas. Tech.
14-3-3 protein interaction modulators Dose Response Confirmation
IC50
>50000±n/a nM
Citation
 PubChem, PC 14-3-3 protein interaction modulators Dose Response Confirmation PubChem Bioassay (2007)[AID] 
Target
Name:
14-3-3 protein gamma
Synonyms:
1433G_HUMAN | YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28289.17
Organism:
Homo sapiens (Human)
Description:
gi_21464101
Residue:
247
Sequence:
MVDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKVFYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSVFYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDDGGEGNN
  
Inhibitor
Name:
BDBM39888
Synonyms:
MLS000110897 | N-methyl-2-phenyl-2-(phenylthio)acetamide | N-methyl-2-phenyl-2-phenylsulfanyl-ethanamide | N-methyl-2-phenyl-2-phenylsulfanylacetamide | SMR000106826 | cid_2889858
Type:
Small organic molecule
Emp. Form.:
C15H15NOS
Mol. Mass.:
257.351
SMILES:
CNC(=O)C(Sc1ccccc1)c1ccccc1
Structure:
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