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Target
Collagenase 3
Ligand
BDBM40470
Substrate
n/a
Meas. Tech.
Dose-response biochemical assay for inhibitors of Matrix Metalloproteinase 13 (MMP13) activity
IC50
>39840±n/a nM
Citation
 PubChem, PC Dose-response biochemical assay for inhibitors of Matrix Metalloproteinase 13 (MMP13) activity PubChem Bioassay (2007)[AID] 
Target
Name:
Collagenase 3
Synonyms:
MMP-13 | MMP13 | MMP13_HUMAN | Matrix metalloproteinase-13 | Matrix metalloproteinase-13 (MMP-13) | Matrix metalloproteinase-13 (MMP13)
Type:
Enzyme
Mol. Mass.:
53808.06
Organism:
Homo sapiens (Human)
Description:
P45452
Residue:
471
Sequence:
MHPGVLAAFLFLSWTHCRALPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENAASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC
  
Inhibitor
Name:
BDBM40470
Synonyms:
5-[2-[(5-chloranylpyridin-2-yl)amino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-amine | 5-[2-[(5-chloro-2-pyridinyl)amino]-4-thiazolyl]-4-methyl-2-thiazolamine | 5-[2-[(5-chloropyridin-2-yl)amino]-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-amine | MLS000064862 | N~2~-(5-chloro-2-pyridinyl)-4'-methyl-4,5'-bi-1,3-thiazole-2,2'-diamine | SMR000077821 | [4-(2-amino-4-methyl-thiazol-5-yl)thiazol-2-yl]-(5-chloro-2-pyridyl)amine | cid_973127
Type:
Small organic molecule
Emp. Form.:
C12H10ClN5S2
Mol. Mass.:
323.824
SMILES:
Cc1nc(N)sc1-c1csc(Nc2ccc(Cl)cn2)n1
Structure:
Search PDB for entries with ligand similarity: