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Target
Complement C1s subcomponent
Ligand
BDBM40797
Substrate
n/a
Meas. Tech.
Complement factor C1s IC50 from mixture screen
IC50
>50000±0 nM
Citation
 PubChem, PC Complement factor C1s IC50 from mixture screen PubChem Bioassay (2008)[AID] 
Target
Name:
Complement C1s subcomponent
Synonyms:
C1 esterase | C1S | C1S_HUMAN | Complement C1s | Complement C1s subcomponent | Complement C1s subcomponent heavy chain | Complement C1s subcomponent light chain | Complement component 1 subcomponent s | Trypsin | complement component 1, s subcomponent
Type:
Protein
Mol. Mass.:
76657.91
Organism:
Homo sapiens (Human)
Description:
P09871
Residue:
688
Sequence:
MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED
  
Inhibitor
Name:
BDBM40797
Synonyms:
MLS000075926 | N-(5-Chloro-2-methoxy-phenyl)-3-(4-o-tolyl-piperazin-1-yl)-propionamide | N-(5-chloranyl-2-methoxy-phenyl)-3-[4-(2-methylphenyl)piperazin-1-yl]propanamide | N-(5-chloro-2-methoxy-phenyl)-3-[4-(o-tolyl)piperazino]propionamide | N-(5-chloro-2-methoxyphenyl)-3-[4-(2-methylphenyl)-1-piperazinyl]propanamide | N-(5-chloro-2-methoxyphenyl)-3-[4-(2-methylphenyl)piperazin-1-yl]propanamide | SMR000011255 | cid_651119
Type:
Small organic molecule
Emp. Form.:
C21H26ClN3O2
Mol. Mass.:
387.903
SMILES:
COc1ccc(Cl)cc1NC(=O)CCN1CCN(CC1)c1ccccc1C
Structure:
Search PDB for entries with ligand similarity: