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Target
Complement C1s subcomponent
Ligand
BDBM40886
Substrate
n/a
Meas. Tech.
Complement factor C1s IC50 from mixture screen
IC50
37870±3770 nM
Citation
 PubChem, PC Complement factor C1s IC50 from mixture screen PubChem Bioassay (2008)[AID] 
Target
Name:
Complement C1s subcomponent
Synonyms:
C1 esterase | C1S | C1S_HUMAN | Complement C1s | Complement C1s subcomponent | Complement C1s subcomponent heavy chain | Complement C1s subcomponent light chain | Complement component 1 subcomponent s | Trypsin | complement component 1, s subcomponent
Type:
Protein
Mol. Mass.:
76657.91
Organism:
Homo sapiens (Human)
Description:
P09871
Residue:
688
Sequence:
MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTYGLYTRVKNYVDWIMKTMQENSTPRED
  
Inhibitor
Name:
BDBM40886
Synonyms:
3-(2-furanyl)-4-oxido-1-(2-pyridinylmethoxy)-2-quinoxalin-4-iumone | 3-(2-furyl)-1-(2-pyridinylmethoxy)-2(1H)-quinoxalinone 4-oxide | 3-(2-furyl)-4-oxido-1-(2-pyridylmethoxy)quinoxalin-4-ium-2-one | 3-(furan-2-yl)-4-oxidanidyl-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one | 3-(furan-2-yl)-4-oxido-1-(pyridin-2-ylmethoxy)quinoxalin-4-ium-2-one | MLS000063818 | SMR000075680 | cid_977079
Type:
Small organic molecule
Emp. Form.:
C18H13N3O4
Mol. Mass.:
335.3135
SMILES:
[O-][n+]1c(-c2ccco2)c(=O)n(OCc2ccccn2)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: