Reaction Details Report a problem with these data
Target
Cathepsin S
Ligand
BDBM41350
Substrate
n/a
Meas. Tech.
Cathepsin S dose-response confirmation
IC50
>50000±0 nM
Citation
 PubChem, PC Cathepsin S dose-response confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM41350
Synonyms:
MLS000052635 | SMR000082217 | cid_1519739 | phenyl-(4-piperazin-1-ylphenyl)methanone | phenyl-(4-piperazinophenyl)methanone | phenyl-[4-(1-piperazinyl)phenyl]methanone | phenyl[4-(1-piperazinyl)phenyl]methanone
Type:
Small organic molecule
Emp. Form.:
C17H18N2O
Mol. Mass.:
266.3376
SMILES:
O=C(c1ccccc1)c1ccc(cc1)N1CCNCC1
Structure:
Search PDB for entries with ligand similarity: