Reaction Details Report a problem with these data
Target
Galanin receptor type 2
Ligand
BDBM37026
Substrate
n/a
Meas. Tech.
Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity
IC50
>42000±n/a nM
Citation
 PubChem, PC Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM37026
Synonyms:
4-(1,3-dioxoisoindol-2-yl)butyl 4-acetyl-3,5-dimethyl-1H-pyrrole-2-carboxylate | 4-[1,3-bis(oxidanylidene)isoindol-2-yl]butyl 4-ethanoyl-3,5-dimethyl-1H-pyrrole-2-carboxylate | 4-acetyl-3,5-dimethyl-1H-pyrrole-2-carboxylic acid 4-(1,3-dioxo-2-isoindolyl)butyl ester | 4-acetyl-3,5-dimethyl-1H-pyrrole-2-carboxylic acid 4-phthalimidobutyl ester | MLS000053810 | SMR000068143 | cid_2535819
Type:
Small organic molecule
Emp. Form.:
C21H22N2O5
Mol. Mass.:
382.4098
SMILES:
CC(=O)c1c(C)[nH]c(C(=O)OCCCCN2C(=O)c3ccccc3C2=O)c1C
Structure:
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