Reaction Details Report a problem with these data
Target
Galanin receptor type 2
Ligand
BDBM42044
Substrate
n/a
Meas. Tech.
Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity
IC50
>42000±n/a nM
Citation
 PubChem, PC Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity PubChem Bioassay (2008)[AID] 
Target
Name:
Galanin receptor type 2
Synonyms:
GALNR2 | GALR2 | GALR2_HUMAN | Galanin R2 | Galanin receptor 2 | Galanin receptor type 2 | Galanin receptor type 2 (GAL2-R) (GALR2).
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41724.40
Organism:
Homo sapiens (Human)
Description:
Galanin R2 GALR2 HUMAN::O43603
Residue:
387
Sequence:
MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA
  
Inhibitor
Name:
BDBM42044
Synonyms:
4-[3-[4-(4-bromophenyl)-4-hydroxy-1-piperidinyl]-2,5-dioxo-1-pyrrolidinyl]benzoic acid ethyl ester | 4-[3-[4-(4-bromophenyl)-4-hydroxy-piperidino]-2,5-diketo-pyrrolidino]benzoic acid ethyl ester | MLS000533866 | SMR000141303 | cid_2884923 | ethyl 4-[3-[4-(4-bromophenyl)-4-hydroxypiperidin-1-yl]-2,5-dioxopyrrolidin-1-yl]benzoate | ethyl 4-[3-[4-(4-bromophenyl)-4-oxidanyl-piperidin-1-yl]-2,5-bis(oxidanylidene)pyrrolidin-1-yl]benzoate | ethyl 4-{3-[4-(4-bromophenyl)-4-hydroxy-1-piperidinyl]-2,5-dioxo-1-pyrrolidinyl}benzoate
Type:
Small organic molecule
Emp. Form.:
C24H25BrN2O5
Mol. Mass.:
501.37
SMILES:
CCOC(=O)c1ccc(cc1)-n1c(O)cc(N2CCC(O)(CC2)c2ccc(Br)cc2)c1O
Structure:
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