Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase YopH
Ligand
BDBM42250
Substrate
n/a
Meas. Tech.
YopH - IC50 determinations (10 point dose range)
IC50
>50000±n/a nM
Citation
 PubChem, PC YopH - IC50 determinations (10 point dose range) PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase YopH
Synonyms:
YOPH_YEREN | yop51 | yopH
Type:
PROTEIN
Mol. Mass.:
50951.99
Organism:
Yersinia enterocolitica
Description:
ChEMBL_965525
Residue:
468
Sequence:
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
  
Inhibitor
Name:
BDBM42250
Synonyms:
2-(2-oxidanylidene-2-phenothiazin-10-yl-ethyl)sulfanylbenzoic acid | 2-(2-oxo-2-phenothiazin-10-ylethyl)sulfanylbenzoic acid | 2-[(2-keto-2-phenothiazin-10-yl-ethyl)thio]benzoic acid | 2-[[2-oxo-2-(10-phenothiazinyl)ethyl]thio]benzoic acid | MLS000418633 | SMR000247547 | cid_2385059
Type:
Small organic molecule
Emp. Form.:
C21H15NO3S2
Mol. Mass.:
393.479
SMILES:
OC(=O)c1ccccc1SCC(=O)N1c2ccccc2Sc2ccccc12
Structure:
Search PDB for entries with ligand similarity: