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Target
Neuropeptide Y receptor type 2
Ligand
BDBM42437
Substrate
n/a
Meas. Tech.
Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism
IC50
>35000±n/a nM
Citation
 PubChem, PC Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM42437
Synonyms:
1-[1-acetyl-5-(4-chlorophenyl)-6-(4-methoxyphenyl)-2-methyl-1,2,5,6-tetrahydro-1,2,4,5-tetrazin-3-yl]ethanone | 1-[2-acetyl-4-(4-chlorophenyl)-3-(4-methoxyphenyl)-1-methyl-3H-1,2,4,5-tetrazin-6-yl]ethanone | 1-[4-(4-chlorophenyl)-2-ethanoyl-3-(4-methoxyphenyl)-1-methyl-3H-1,2,4,5-tetrazin-6-yl]ethanone | MLS000727503 | SMR000306200 | cid_539575
Type:
Small organic molecule
Emp. Form.:
C20H21ClN4O3
Mol. Mass.:
400.859
SMILES:
COc1ccc(cc1)C1N(N=C(N(C)N1C(C)=O)C(C)=O)c1ccc(Cl)cc1 |c:11|
Structure:
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