Reaction Details Report a problem with these data
Target
Cell division control protein 42 homolog
Ligand
BDBM43207
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
EC50
5854±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM43207
Synonyms:
2-[(2,6-dichlorobenzyl)amino]-3-methyl-butyric acid | 2-[(2,6-dichlorophenyl)methylamino]-3-methylbutanoic acid | 2-[[2,6-bis(chloranyl)phenyl]methylamino]-3-methyl-butanoic acid | MLS000095936 | N-(2,6-dichlorobenzyl)valine | SMR000031484 | cid_3237092
Type:
Small organic molecule
Emp. Form.:
C12H15Cl2NO2
Mol. Mass.:
276.159
SMILES:
CC(C)C(NCc1c(Cl)cccc1Cl)C(O)=O
Structure:
Search PDB for entries with ligand similarity: