Reaction Details Report a problem with these data
Target
Cell division control protein 42 homolog
Ligand
BDBM43209
Substrate
n/a
Meas. Tech.
Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant
EC50
15440±n/a nM
Citation
 PubChem, PC Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant PubChem Bioassay (2010)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM43209
Synonyms:
1-(3-methoxyphenyl)-5-(methylsulfonyl)-1H-tetrazole | 1-(3-methoxyphenyl)-5-methylsulfonyl-1,2,3,4-tetrazole | 1-(3-methoxyphenyl)-5-methylsulfonyltetrazole | 5-mesyl-1-(3-methoxyphenyl)tetrazole | MLS000537345 | SMR000143783 | cid_2221997
Type:
Small organic molecule
Emp. Form.:
C9H10N4O3S
Mol. Mass.:
254.266
SMILES:
COc1cccc(c1)-n1nnnc1S(C)(=O)=O
Structure:
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