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Target
Wee1-like protein kinase
Ligand
BDBM43761
Substrate
n/a
Meas. Tech.
Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation
EC50
>49750±n/a nM
Citation
 PubChem, PC Dose Response Cell-based Assay for Inhibitors of Wee1 Degradation PubChem Bioassay (2008)[AID] 
Target
Name:
Wee1-like protein kinase
Synonyms:
Serine/threonine-protein kinase WEE1 | WEE1 | WEE1 homolog (S. pombe) | WEE1_HUMAN
Type:
PROTEIN
Mol. Mass.:
71599.12
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1445054
Residue:
646
Sequence:
MSFLSRQQPPPPRRAGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQEPDSPLPPARSPTEPGPERRRSPGPAPGSPGELEEDLLLPGACPGADEAGGGAEGDSWEEEGFGSSSPVKSPAAPYFLGSSFSPVRCGGPGDASPRGCGARRAGEGRRSPRPDHPGTPPHKTFRKLRLFDTPHTPKSLLSKARGIDSSSVKLRGSSLFMDTEKSGKREFDVRQTPQVNINPFTPDSLLLHSSGQCRRRKRTYWNDSCGEDMEASDYELEDETRPAKRITITESNMKSRYTTEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPLAGSVDEQNALREVYAHAVLGQHSHVVRYFSAWAEDDHMLIQNEYCNGGSLADAISENYRIMSYFKEAELKDLLLQVGRGLRYIHSMSLVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISSPQVEEGDSRFLANEVLQENYTHLPKADIFALALTVVCAAGAEPLPRNGDQWHEIRQGRLPRIPQVLSQEFTELLKVMIHPDPERRPSAMALVKHSVLLSASRKSAEQLRIELNAEKFKNSLLQKELKKAQMAKAAAEERALFTDRMATRSTTQSNRTSRLIGKKMNRSVSLTIY
  
Inhibitor
Name:
BDBM43761
Synonyms:
2-methoxy-5-[2-(2-naphthoyl)carbohydrazonoyl]phenyl 4-(acetylamino)benzenesulfonate | 4-acetamidobenzenesulfonic acid [2-methoxy-5-[(2-naphthoylhydrazono)methyl]phenyl] ester | 4-acetamidobenzenesulfonic acid [2-methoxy-5-[[[2-naphthalenyl(oxo)methyl]hydrazinylidene]methyl]phenyl] ester | MLS000541168 | SMR000160961 | [2-methoxy-5-[(naphthalen-2-ylcarbonylhydrazinylidene)methyl]phenyl] 4-acetamidobenzenesulfonate | [2-methoxy-5-[(naphthalene-2-carbonylhydrazinylidene)methyl]phenyl] 4-acetamidobenzenesulfonate | cid_4384243
Type:
Small organic molecule
Emp. Form.:
C27H23N3O6S
Mol. Mass.:
517.553
SMILES:
COc1ccc(C=NNC(=O)c2ccc3ccccc3c2)cc1OS(=O)(=O)c1ccc(NC(C)=O)cc1 |w:7.7|
Structure:
Search PDB for entries with ligand similarity: